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001			5000214
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007			cr||||||||||||
008			100301s2008 gw | s |||| 0|eng d
020			_a9783540767848
024	7		_a10.1007/978-3-540-76784-8 _2doi
035			_a978-3-540-76784-8
072		7	_aPBW _2bicssc
072		7	_aMAT003000 _2bisacsh
082	0	4	_a570.151
090			_amg
100	0		_aMondaini, Rubem P. _99240
245	1	0	_aMathematical Modelling of Biosystems _h[electronic resource]/ _cedited by Rubem P. Mondaini, Panos M. Pardalos.
260			_aBerlin, Heidelberg: _bSpringer Berlin Heidelberg, _c2008.
300			_bdigital.
490	0		_aApplied Optimization, _x1384-6485; _v102
505	0		_aElastic Growth Models -- A Model of Pattern Coupled to Form in Metazoans -- Mathematical Modelling HIV-I Infection and Drug Therapy -- Overcoming the Key Challenges in De Novo Protein Design: Enhancing Computational Efficiency and Incorporating True Backbone Flexibility -- An Improves Heuristic for Consistent Biclustering Problems -- The Steiner Tree Problem and Its Application to the Modelling of Biomolecular Structures -- Phenotypic Switching and Mutation in the Presence of a Biocide: No Replication of Phenotypic Variant -- From Spatial Pattern in the Distribution and Abundance of Species to a Unified Theory of Ecology: The Role of Maximum Entropy Methods -- Protein Structure and Its Folding Rate .
520			_aThis volume is an interdisciplinary book, which introduces, in a very readable way, state of the art research in the fundamental topics of mathematical modelling of Biosystems. These topics include: the study of Biological Growth and its mechanisms, the coupling of pattern to form via theorems of Differential Geometry, the human immunodeficiency virus dynamics, the inverse folding problem and the possibility of analysing true protein backbone flexibility, the Biclustering techniques for the organization of microarray data, the analytical approach to the modelling of biomolecular structure via Steiner trees, the action of biocides on resistance mechanisms of mutated and phenotypic bacteria strains, a description of the fundamental processes for the distribution and abundances of species towards a unified theory of Ecology, and a special introduction to Protein Physics aiming to explain the all-or-none first order phase transitions from native to denatured states .
650		0	_aMathematics _943458
650		0	_aLife sciences _xMathematics. _922857
650		0	_aCytology. _927975
650		0	_aBiology _xMathematics _99085
697			_aMatemáticas Gerais- _x(inclusive alguns textos elementares sobre assuntos específicos) _923752
700	1		_aPardalos, P. M. _q(Panos M.), _d1954- _943402
710	1		_aSpringerLink (Online service). _98857
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9783540767831
830		0	_aApplied optimization; _v102 _936401
856	4	0	_uhttp://dx.doi.org/10.1007/978-3-540-76784-8
942			_2impa _cEBK
999			_aMONDAINI, Rubem P.; PARDALOS, P. M. <b> Mathematical Modelling of Biosystems. </b> Berlin, Heidelberg: Springer Berlin Heidelberg, 2008. (Applied Optimization, 1384-6485 ; 102). ISBN 9783540767848. Disponível em: <http://dx.doi.org/10.1007/978-3-540-76784-8 > _c38586 _d38586