Bioconductor Case Studies (Record no. 38513)

MARC details
000 -LEADER
fixed length control field 04343n a2200517#a 4500
001 - CONTROL NUMBER
control field 5000086
003 - CONTROL NUMBER IDENTIFIER
control field DE-He213
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20221213140638.0
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
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008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 100608s2008 xxu| s |||| 0|eng d
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9780387772400
024 7# - OTHER STANDARD IDENTIFIER
Standard number or code 10.1007/978-0-387-77240-0
Source of number or code doi
035 ## - SYSTEM CONTROL NUMBER
System control number 978-0-387-77240-0
072 #7 - SUBJECT CATEGORY CODE
Subject category code PBT
Source bicssc
072 #7 - SUBJECT CATEGORY CODE
Subject category code MBNS
Source bicssc
072 #7 - SUBJECT CATEGORY CODE
Subject category code MED090000
Source bisacsh
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 519.5
090 ## - IMPA CODE FOR CLASSIFICATION SHELVES
IMPA CODE FOR CLASSIFICATION SHELVES Matemáticas Gerais-(inclusive alguns textos elementares sobre assuntos específicos)
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Hahne, Florian
9 (RLIN) 9108
245 10 - TITLE STATEMENT
Title Bioconductor Case Studies
Medium [electronic resource]/
Statement of responsibility, etc. by Florian Hahne, Wolfgang Huber, Robert Gentleman, Seth Falcon.
250 ## - EDITION STATEMENT
Edition statement 1.
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Place of publication, distribution, etc. New York:
Name of publisher, distributor, etc. Springer New York,
Date of publication, distribution, etc. 2008.
300 ## - PHYSICAL DESCRIPTION
Other physical details digital.
490 0# - SERIES STATEMENT
Series statement Use R!
505 0# - FORMATTED CONTENTS NOTE
Formatted contents note The ALL data set -- R and Bioconductor introduction -- Processing affymetrix expression data -- Two color arrays -- Fold changes, log-ratios, background correction, shrinkage estimation and variance stabilization -- Easy differential expression -- Differential expression -- Annotation and metadata -- Supervised machine learning -- Unsupervised machine learning -- Using graphs for interactome data -- Graph layout -- Gene set enrichment analysis -- Hypergeometric testing used for gene set enrichment analysis -- Solutions to exercises -- References -- Index .
520 ## - SUMMARY, ETC.
Summary, etc. Bioconductor software has become a standard tool for the analysis and comprehension of data from high-throughput genomics experiments. Its application spans a broad field of technologies used in contemporary molecular biology. In this volume, the authors present a collection of cases to apply Bioconductor tools in the analysis of microarray gene expression data. Topics covered include * import and preprocessing of data from various sources * statistical modeling of differential gene expression * biological metadata * application of graphs and graph rendering * machine learning for clustering and classification problems * gene set enrichment analysis Each chapter of this book describes an analysis of real data using hands-on example driven approaches. Short exercises help in the learning process and invite more advanced considerations of key topics. The book is a dynamic document. All the code shown can be executed on a local computer, and readers are able to reproduce every computation, figure, and table. The authors of this book have longtime experience in teaching introductory and advanced courses to the application of Bioconductor software. Florian Hahne is a Postdoc at the Fred Hutchinson Cancer Research Center in Seattle, developing novel methodologies for the analysis of high-throughput cell-biological data. Wolfgang Huber is a research group leader in the European Molecular Biology Laboratory at the European Bioinformatics Institute in Cambridge. He has wide-ranging experience in the development of methods for the analysis of functional genomics experiments. Robert Gentleman is Head of the Program in Computational Biology at the Fred Hutchinson Cancer Research Center in Seattle, and he is one of the two authors of the original R system. Seth Falcon is a member of the R core team and former project manager and developer for the Bioconductor project .
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Statistics.
9 (RLIN) 43790
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Bioinformatics.
9 (RLIN) 16927
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Biology
General subdivision Mathematics
9 (RLIN) 9085
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Statistics.
9 (RLIN) 43790
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Statistics for Life Sciences, Medicine, Health Sciences
9 (RLIN) 8874
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Computational Biology/Bioinformatics
9 (RLIN) 9111
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Bioinformatics.
9 (RLIN) 16927
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Mathematical Biology in General
9 (RLIN) 9112
697 ## - LOCAL SUBJECT
Local Subject Matemáticas Gerais-
Description subdivision (inclusive alguns textos elementares sobre assuntos específicos)
Linkage 23752
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Huber, Wolfgang
9 (RLIN) 9113
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Gentleman, Robert
9 (RLIN) 9114
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Falcon, Seth
9 (RLIN) 9115
710 1# - ADDED ENTRY--CORPORATE NAME
Corporate name or jurisdiction name as entry element SpringerLink (Online service).
9 (RLIN) 8857
773 0# - HOST ITEM ENTRY
Title Springer eBooks
776 08 - ADDITIONAL PHYSICAL FORM ENTRY
Relationship information Printed edition:
International Standard Book Number 9780387772 394
830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE
Uniform title Use R!
9 (RLIN) 9117
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="http://dx.doi.org/10.1007/978-0-387-77240-0">http://dx.doi.org/10.1007/978-0-387-77240-0</a>
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Instituto de Matemática Pura e Aplicada
Koha item type E-Book

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